Sphenopalatine Ganglion (SPG) Block

A sphenopalatine ganglion (SPG) block is a minimally invasive procedure used to treat chronic headaches and facial pain. The treatment involves delivering a local anesthetic to the sphenopalatine ganglion, a cluster of nerve cells located behind the nasal cavity that plays a central role in headache disorders.

The SPG is connected to the trigeminal nerve, a major nerve involved in migraines, cluster headaches, and trigeminal neuralgia. Blocking this nerve bundle can significantly reduce pain transmission.

What Is an SPG Block?

The sphenopalatine ganglion contains:

  1. Sensory nerves that transmit pain signals
  2. Autonomic nerves that regulate nasal congestion and tear production

Because the SPG communicates with the trigeminal nerve and brainstem, it is a key target in the treatment of headache disorders and certain types of facial pain.

An SPG block involves applying a local anesthetic to temporarily block pain signals transmitted through the sphenopalatine ganglion.

The procedure works by:

Conditions Treated

SPG blocks are effective for:

  • Migraines
  • Cluster headaches
  • Trigeminal neuralgia
  • Paroxysmal hemicrania
  • Trigeminal neuropathy (atypical facial pain)
  • Chronic daily headaches

Patients who do not respond adequately to oral medications may benefit from SPG block therapy.

Symptoms of Upper Cervical Joint Dysfunction

Patients suitable for SPG block often experience:

  • Severe unilateral headaches
  • Facial pain
  • Headaches associated with nasal congestion
  • Tearing of the eyes
  • Burning or electric-like facial pain

These symptoms are commonly associated with trigeminal and autonomic activation.

Table of Contents

How the Procedure Is Performed

SPG blocks are performed in an outpatient setting and typically take only a few minutes.

Delivery methods include:

  1. Cotton-tipped applicator placed through the nose to reach the SPG
  2. Thin, flexible catheter inserted intranasally to deliver anesthetic
  3. Image-guided injection through the cheek (less common and more invasive)

The intranasal catheter technique is commonly preferred because it is less invasive and does not require fluoroscopy.

Benefits of SPG Block


Frequently Asked Questions

How does a stellate ganglion block relieve pain?

A stellate ganglion block is used to treat Complex Regional Pain Syndrome (CRPS), nerve injury pain, shingles, and sympathetically mediated pain affecting the head, neck, chest, or arm.

The procedure typically takes about 30 minutes and is performed in an outpatient setting under imaging guidance.

Some patients experience pain relief within minutes. Depending on the condition, a series of injections may be needed for longer-lasting results.

Relief may last from days to months, depending on the severity of CRPS or nerve-related pain.

Begin your journey to recovery.

Reach out to our specialists to schedule an initial consultation. We’ll carefully review your symptoms and match you with the right expert for your specific condition.

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